🏛️ Verified NIH Protocol • Sourced via U.S. National Library of Medicine (Last Synced: 2026-08-25)

A Study of Secutrelvir in Participants With Coronavirus Disease 2019 (COVID-19) Who Are at High Risk for Progression to Severe Disease

🟢 Recruiting Phase 3 💊 Investigational Drug / Biologic Sponsor: Shionogi

🩺 Protocol Summary

The primary purpose of this study is to evaluate the efficacy and safety of secutrelvir in symptomatic nonhospitalized adult and adolescent participants with COVID-19 who are at high risk for progression to severe disease.

Primary Research Facility: Hope Clinical Trials - 3970 W Flagler St. (Coral Gables, Florida)

📋 Basic Study Criteria & Logistics Checklist

0 of 3 Checked

Review these 3 basic logistical and protocol criteria extracted from the public NIH record. (This is a preliminary logistical checklist, not an official clinical eligibility determination).

Diagnosed with, undergoing evaluation for, or seeking treatment related to SARS-CoV-2?

🔍 Study Population / Focus Area (Source: Protocol Primary Condition)

Aged 12 Years or older?

🔍 Protocol Specified Minimum Age: 12 Years

Able to attend required in-person clinic visits and study procedures at one of the participating study centers?

🔍 Logistical Requirement: 27 Registered Participating Sites

📍 Primary Site Map

Site: Hope Clinical Trials - 3970 W Flagler St. — Coral Gables, Florida

📍 All Participating Trial Locations (27 Sites)

Multi-Center Trial

This protocol is enrolling participants across multiple clinical centers:

1. Hope Clinical Trials - 3970 W Flagler St. — Coral Gables, Florida

2. Continental Clinical Research, LLC — Miami, Florida

3. Reed Medical Research — Miami, Florida

4. Kendall South Medical Center Inc. — Miami, Florida

5. Global Clinical Professionals — St. Petersburg, Florida

6. New Tampa Health — Tampa, Florida

7. Research Bay, Inc. — Tampa, Florida

8. Hometown Urgent Care and Research — Cincinnati, Ohio

9. Medical Center Unimed EOOD — Sevlievo, Gabrovo

10. Medichi Sofia - Medical Center OOD — Sofia, Sofia

11. MCpulmo-2018 Ltd — United States

12. Medical Center Medconsult Pleven - Lovech Branch — United States

13. Medical Center Medconsult Pleven OOD — United States

14. Abe Shun Naika Clinic — Kasugai-Shi, Aiti

15. Chiba Aoba Municipal Hospital — Chiba, Chiba

16. Japan Community Health Care Organization Nihonmatsu Hospital — Nihommatsu, Fukushima

17. Tsuchiura Beryl Clinic — Takasaki-shi, Gunma

18. Toda Internal Medicine & Neurology — Akashi-Shi, Hyôgo

19. Terada Clinic Respiratory Medicine and General Practice — Himeji-shi, Hyôgo

20. Kamezawa Clinic — Tsuchiura-Shi, Ibaraki

21. Sato Clinic — Kawasaki-shi, Kanagawa

22. Shibasaki Internal Medicine and Pediatrics Clinic — Sendai, Miyagi

23. Tokyo Center Clinic — Chuo-Ku, Tokyo

24. Shizuka Medicine Clinic — Musashino, Tokyo

25. Yotsuya Naika — Shibuya-Ku, Tokyo

📄 Print Doctor Discussion Sheet

Preview and print a 1-page summary with 5 tailored questions for your physician.

💰 Clinical Trial Costs & Insurance Coverage

Coverage for clinical trial participation varies depending on your health insurance policy, state legislation, and whether specific procedures are investigational research or routine medical care. Under federal law (Affordable Care Act § 2709), health insurers generally cannot drop coverage or refuse to pay for routine patient care costs incurred in approved clinical trials.

💡 Always ask the study coordinator for the trial's official Informed Consent Form, which outlines all sponsor-funded research items versus procedures billed to your insurance.

🏛️ Official Government Provenance

NIH ClinicalTrials.gov Protocol Record

NCT Identifier: NCT07743580 • Last Synced: 2026-08-25

View on ClinicalTrials.gov ↗