🏛️ Verified NIH Protocol • Sourced via U.S. National Library of Medicine (Last Synced: 2026-08-12)

ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection

🟢 Recruiting Phase 2 💊 Investigational Drug / Biologic Sponsor: Acurx Pharmaceuticals Inc.

🩺 Protocol Summary

Single-arm trial to evaluate the safety and efficacy of ACX-362E \[ibezapolstat\] in patients with recurrent C. difficile infection (CDI).

Primary Research Facility: UC Davis Medical Center (Sacramento, California)

📋 Basic Study Criteria & Logistics Checklist

0 of 3 Checked

Review these 3 basic logistical and protocol criteria extracted from the public NIH record. (This is a preliminary logistical checklist, not an official clinical eligibility determination).

Diagnosed with, undergoing evaluation for, or seeking treatment related to Clostridium Difficile Infection Recurrence?

🔍 Study Population / Focus Area (Source: Protocol Primary Condition)

Aged between 18 Years and 90 Years?

🔍 Protocol Specified Age Range: 18 Years to 90 Years

Able to attend required in-person clinic visits and study procedures at one of the participating study centers?

🔍 Logistical Requirement: 15 Registered Participating Sites

📍 Primary Site Map

Site: UC Davis Medical Center — Sacramento, California

📍 All Participating Trial Locations (15 Sites)

Multi-Center Trial

This protocol is enrolling participants across multiple clinical centers:

1. UC Davis Medical Center — Sacramento, California

2. Gastroenterolgy Center of Conneticut — Hamden, Connecticut

3. Florida International Medical Research — Coral Gables, Florida

4. L&A Morales Healthcare, Inc — Hialeah, Florida

5. San Marcus Research Clinc, Inc — Miami Lakes, Florida

6. Belis Delgado, MD PA — Miami Springs, Florida

7. Infectious Disease Consultants of Georgia — Athens, Georgia

8. Snake River Research PLLC — Idaho Falls, Idaho

9. Endevour Health — Skokie, Illinois

10. Newton-Wellesley Hospital — Newton, Massachusetts

11. University of Massachusetts Memorial Healthcare — Worcester, Massachusetts

12. Henry Ford Hospital — Detroit, Michigan

13. DiGiovanna Institute for Medical Education and Research — Massapequa, New York

14. Romano, Pontzer & Associated — Pittsburgh, Pennsylvania

15. University of Utah — Salt Lake City, Utah

📄 Print Doctor Discussion Sheet

Preview and print a 1-page summary with 5 tailored questions for your physician.

💰 Clinical Trial Costs & Insurance Coverage

Coverage for clinical trial participation varies depending on your health insurance policy, state legislation, and whether specific procedures are investigational research or routine medical care. Under federal law (Affordable Care Act § 2709), health insurers generally cannot drop coverage or refuse to pay for routine patient care costs incurred in approved clinical trials.

💡 Always ask the study coordinator for the trial's official Informed Consent Form, which outlines all sponsor-funded research items versus procedures billed to your insurance.

🏛️ Official Government Provenance

NIH ClinicalTrials.gov Protocol Record

NCT Identifier: NCT07513285 • Last Synced: 2026-08-12

View on ClinicalTrials.gov ↗