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πŸ›οΈ Verified NIH Protocol β€’ Sourced via U.S. National Library of Medicine (Last Synced: 2026-08-28)

Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation

🟒 Recruiting Phase 3 πŸ’Š Investigational Drug / Biologic Sponsor: Syndax Pharmaceuticals

🩺 Protocol Summary

The purpose of this study is to assess if adding revumenib to standard chemotherapy improves outcomes in participants with AML with certain genetic mutations compared to chemotherapy alone. The study will also assess the safety of adding revumenib to chemotherapy.

Primary Research Facility: Clinical Trial Site (Goodyear, Arizona)

πŸ“‹ Basic Study Criteria & Logistics Checklist

0 of 3 Checked

Review these 3 basic logistical and protocol criteria extracted from the public NIH record. (This is a preliminary logistical checklist, not an official clinical eligibility determination).

πŸ“ Primary Site Map

Site: Clinical Trial Site β€” Goodyear, Arizona

πŸ“ All Participating Trial Locations (109 Sites)

Multi-Center Trial

This protocol is enrolling participants across multiple clinical centers:

1. Clinical Trial Site β€” Goodyear, Arizona
2. Clinical Trial Site β€” Duarte, California
3. Clinical Trial Site β€” Shreveport, Louisiana
4. Clinical Trial Site β€” South Brisbane, Queensland
5. Clinical Trial Site β€” Melbourne, Victoria
6. Clinical Trial Site β€” Nedlands, Western Australia
7. Clinical Trial Site β€” Perth, Western Australia
8. Clinical Trial Site β€” United States
9. Clinical Trial Site β€” United States
10. Clinical Trial Site β€” Klagenfurt, Kaerten
11. Clinical Trial Site β€” Sankt PΓΆlten, Lower Austria
12. Clinical Trial Site β€” Graz, Styria
13. Clinical Trial Site β€” Leoben, Styria
14. Clinical Trial Site β€” United States
15. Clinical Trial Site β€” United States
16. Clinical Trial Site β€” Fortaleza, ParanΓ‘
17. Clinical Trial Site β€” Barretos, SΓ£o Paulo
18. Clinical Trial Site β€” United States
19. Clinical Trial Site β€” United States
20. Clinical Trial Site β€” United States
21. Clinical Trial Site β€” United States
22. Clinical Trial Site β€” Nice, Alpes-Maritimes
23. Clinical Trial Site β€” Strasbourg, Bas-Rhin
24. Clinical Trial Site β€” Angers, Loire-Atlantique
25. Clinical Trial Site β€” Pessac, Pas-de-Calais

πŸ“„ Print Doctor Discussion Sheet

Preview and print a 1-page summary with 5 tailored questions for your physician.

πŸ’° Clinical Trial Costs & Insurance Coverage

Coverage for clinical trial participation varies depending on your health insurance policy, state legislation, and whether specific procedures are investigational research or routine medical care. Under federal law (Affordable Care Act Β§ 2709), health insurers generally cannot drop coverage or refuse to pay for routine patient care costs incurred in approved clinical trials.

πŸ’‘ Always ask the study coordinator for the trial's official Informed Consent Form, which outlines all sponsor-funded research items versus procedures billed to your insurance.

πŸ›οΈ Official Government Provenance

NIH ClinicalTrials.gov Protocol Record

NCT Identifier: NCT07211958 β€’ Last Synced: 2026-08-28
View on ClinicalTrials.gov β†—
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