Mechanism of Ketogenic Diet-Induced Hypercholesterolemia
๐ฉบ Protocol Summary
Very-low carbohydrate ketogenic diets can dramatically increase blood cholesterol levels, particularly in normal-weight people, for reasons that are not well understood. This study will enroll normal-weight adults, will identify "responders" who develop high cholesterol on a ketogenic diet, and will measure rates of production and removal of certain types of cholesterol-carrying particles called lipoproteins in responders. The results will clarify the mechanism by which a ketogenic diet can cause high cholesterol in certain susceptible people.
Primary Research Facility: Washington University School of Medicine (St Louis, Missouri)
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Site: Washington University School of Medicine โ St Louis, Missouri
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