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🏛️ Verified NIH Protocol • Sourced via U.S. National Library of Medicine (Last Synced: 2026-07-29)

A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

🟢 Recruiting Phase 3 💊 Investigational Drug / Biologic Sponsor: Novartis Pharmaceuticals

🩺 Protocol Summary

A study to evaluate the efficacy, safety and tolerability of Remibrutinib versus placebo in adult patients with Generalized Myasthenia Gravis who are on stable, standard-of-care (SOC) treatment.

Primary Research Facility: Neuromuscular Research Center (Phoenix, Arizona)

📋 Basic Study Criteria & Logistics Checklist

0 of 3 Checked

Review these 3 basic logistical and protocol criteria extracted from the public NIH record. (This is a preliminary logistical checklist, not an official clinical eligibility determination).

📍 Primary Site Map

Site: Neuromuscular Research Center — Phoenix, Arizona

📍 All Participating Trial Locations (130 Sites)

Multi-Center Trial

This protocol is enrolling participants across multiple clinical centers:

1. Neuromuscular Research Center — Phoenix, Arizona
2. Honor Health Research Institute — Scottsdale, Arizona • Contact: (480) 323-3990
3. Fullerton Neuro and Headache Ctr — Fullerton, California • Contact: (714) 738-0800
4. University Of Southern California — Los Angeles, California • Contact: (323) 865-3900
5. Univ Cali Irvine ALS Neuromuscular — Orange, California • Contact: (714) 456-2332
6. California Pacific Medical Center — Sacramento, California • Contact: (415) 600-3604
7. Medstar Washington Hospital Center — Washington D.C., District of Columbia
8. SFM Clinical Research LLC — Boca Raton, Florida • Contact: (561) 939-0300
9. Homestead Assoc In Research Inc — Homestead, Florida • Contact: (305) 246-0873
10. Neurology Associates PA — Maitland, Florida • Contact: (407) 647-5996
11. AdventHealth — Orlando, Florida • Contact: (407) 303-6729
12. Neurological Services of Orlando PA — Orlando, Florida • Contact: (941) 400-4578
13. University of Chicago Medical Centr — Chicago, Illinois
14. Mid Atlantic Epilepsy and Sleep Ctr — Bethesda, Maryland
15. Massachusetts General Hospital — Boston, Massachusetts
16. Michigan State University-Department of Neurology — East Lansing, Michigan
17. Dent Neurological Institute — Buffalo, New York • Contact: (716) 887-4799
18. Univ of Cincinnati Medical Center — Cincinnati, Ohio • Contact: (513) 475-8730
19. Cleveland Clinic Foundation — Cleveland, Ohio
20. University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania • Contact: (412) 692-4920
21. Houston Methodist Hospital — Houston, Texas • Contact: (713) 441-9484
22. UT Health Science Center — Houston, Texas
23. University of WA Division of Cardio — Seattle, Washington • Contact: (206) 685-1048
24. Center for Neurological Disorders G — Greenfield, Wisconsin
25. Novartis Investigative Site — Rosario, Santa Fe Province

📄 Print Doctor Discussion Sheet

Preview and print a 1-page summary with 5 tailored questions for your physician.

💰 Clinical Trial Costs & Insurance Coverage

Coverage for clinical trial participation varies depending on your health insurance policy, state legislation, and whether specific procedures are investigational research or routine medical care. Under federal law (Affordable Care Act § 2709), health insurers generally cannot drop coverage or refuse to pay for routine patient care costs incurred in approved clinical trials.

💡 Always ask the study coordinator for the trial's official Informed Consent Form, which outlines all sponsor-funded research items versus procedures billed to your insurance.

🏛️ Official Government Provenance

NIH ClinicalTrials.gov Protocol Record

NCT Identifier: NCT06744920 • Last Synced: 2026-07-29
View on ClinicalTrials.gov ↗
📞 Call Desk 📋 Check Criteria