Identify the Optimal TMS Pulse Protocol to Modulate Reward Activity

🩺 Protocol Summary

The primary goal will be to identify the optimal pulse protocol by systematically measuring the efficacy of various theta burst stimulation and repetitive rTMS protocols to increase and decrease the reward positivity in dependent smokers. The secondary objective will be to measure the protocols' effectiveness to increase decision-making capacity using the probabilistic selection task (PST). The third objective will be to specifically assess whether the TMS targets has a differential impact on state levels of craving relative to baseline (Tobacco Craving Questionnaire \[TCQ\]. The investigators plan to accomplish these three objectives using a randomized, controlled experiment involving 2 sessions.

Primary Research Facility: Rutgers University - Newark (Newark, New Jersey)

Review these 3 basic logistical and protocol criteria extracted from the public NIH record. (This is a preliminary logistical checklist, not an official clinical eligibility determination).

Diagnosed with, undergoing evaluation for, or seeking treatment related to Nicotine Use Disorder?

🔍 Study Population / Focus Area (Source: Protocol Primary Condition)

Aged between 18 Years and 55 Years?

🔍 Protocol Specified Age Range: 18 Years to 55 Years

Able to attend required clinic visits at Rutgers University - Newark (Newark, New Jersey)?

🔍 Logistical Requirement: Site at Rutgers University - Newark

📍 Primary Site Map

Site: Rutgers University - Newark — Newark, New Jersey

💰 Clinical Trial Costs & Insurance Coverage

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💡 Always ask the study coordinator for the trial's official Informed Consent Form, which outlines all sponsor-funded research items versus procedures billed to your insurance.