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๐Ÿ›๏ธ Verified NIH Protocol โ€ข Sourced via U.S. National Library of Medicine (Last Synced: 2026-07-24)

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

๐ŸŸข Recruiting Phase 1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Xencor, Inc.

๐Ÿฉบ Protocol Summary

The Phase 1 study described herein will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of XmAb942 in healthy volunteers (Parts A and B). Part C of this study will be a Phase 2 study to evaluate XmAb942 in participants with ulcerative colitis (UC).

Primary Research Facility: Xencor Investigative Site (Scottsdale, Arizona)

๐Ÿ“‹ Preliminary Self-Screener

0 of 3 Answered

Answer all 3 basic criteria below to see your preliminary screening result:

๐Ÿ“ Primary Site Map

Site: Xencor Investigative Site โ€” Scottsdale, Arizona

๐Ÿ“ All Participating Trial Locations (90 Sites)

Multi-Center Trial

This protocol is enrolling participants across multiple clinical centers:

1. Xencor Investigative Site โ€” Scottsdale, Arizona
2. Xencor Investigative Site โ€” Bradenton, Florida
3. Xencor Investigative Site โ€” Brandon, Florida
4. Xencor Investigative Site โ€” Jacksonville, Florida
5. Xencor Investigative Site โ€” Kissimmee, Florida
6. Xencor Investigative Site โ€” Margate, Florida
7. Xencor Investigative Site โ€” Palmetto Bay, Florida
8. Xencor Investigative Site โ€” Tampa, Florida
9. Xencor Investigative Site โ€” Tampa, Florida
10. Xencor Investigative Site โ€” Louisville, Kentucky
11. Xencor Investigative Site โ€” Oxford, Mississippi
12. Xencor Investigative Site โ€” Tupelo, Mississippi
13. Xencor Investigative Site โ€” Albany, New York
14. Xencor Investigative Site โ€” Rochester, New York
15. Xencor Investigative Site โ€” Raleigh, North Carolina
16. Xencor Investigative Site โ€” Beavercreek, Ohio
17. Xencor Investigative Site โ€” Cordova, Tennessee
18. Xencor Investigative Site โ€” Cedar Park, Texas
19. Xencor Investigative Site โ€” Denton, Texas
20. Xencor Investigative Site โ€” Garland, Texas
21. Xencor Investigative Site โ€” Georgetown, Texas
22. Xencor Investigative Site โ€” Houston, Texas
23. Xencor Investigative Site โ€” Houston, Texas
24. Xencor Investigative Site โ€” Kingwood, Texas
25. Xencor Investigative Site โ€” Lubbock, Texas

๐Ÿ“„ Print Doctor Discussion Sheet

Preview and print a 1-page summary with 5 tailored questions for your physician.

๐Ÿ’ฐ Clinical Trial Costs & Insurance Coverage

Coverage for clinical trial participation varies depending on your health insurance policy, state legislation, and whether specific procedures are investigational research or routine medical care. Under federal law (Affordable Care Act ยง 2709), health insurers generally cannot drop coverage or refuse to pay for routine patient care costs incurred in approved clinical trials.

๐Ÿ’ก Always ask the study coordinator for the trial's official Informed Consent Form, which outlines all sponsor-funded research items versus procedures billed to your insurance.

๐Ÿ›๏ธ Official Government Provenance

NIH ClinicalTrials.gov Protocol Record

NCT Identifier: NCT06619990 โ€ข Last Synced: 2026-07-24
View on ClinicalTrials.gov โ†—
๐Ÿ›๏ธ NIH Record ๐Ÿ“‹ Check Eligibility