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πŸ›οΈ Verified NIH Protocol β€’ Sourced via U.S. National Library of Medicine (Last Synced: 2026-08-28)

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

🟒 Recruiting Phase 2 πŸ’Š Investigational Drug / Biologic Sponsor: Janssen Research & Development, LLC

🩺 Protocol Summary

The purpose of this study is to identify preventive treatments that can minimize the occurrence, severity, and duration of talquetamab-related taste changes (dysgeusia), during the prophylaxis (preventive) treatment phase, to better characterize the signs or symptoms of talquetamab-related taste changes and to better characterize the signs or symptoms of ramantamig-related taste changes.

Primary Research Facility: University of California San Francisco (San Francisco, California)

πŸ“‹ Basic Study Criteria & Logistics Checklist

0 of 3 Checked

Review these 3 basic logistical and protocol criteria extracted from the public NIH record. (This is a preliminary logistical checklist, not an official clinical eligibility determination).

πŸ“ Primary Site Map

Site: University of California San Francisco β€” San Francisco, California

πŸ“ All Participating Trial Locations (38 Sites)

Multi-Center Trial

This protocol is enrolling participants across multiple clinical centers:

1. University of California San Francisco β€” San Francisco, California
2. Colorado Blood Cancer Institute β€” Denver, Colorado
3. Yale University School Of Medicine β€” New Haven, Connecticut
4. Icahn School of Medicine at Mt. Sinai β€” New York, New York
5. University of Rochester Medical Center β€” Rochester, New York
6. Duke University Medical Center β€” Durham, North Carolina
7. University Hospitals Cleveland Medical Center β€” Cleveland, Ohio
8. Virginia Commonwealth University - Massey Cancer Center β€” Richmond, Virginia
9. University of Washington β€” Seattle, Washington
10. IDOR - Regional Brasilia β€” United States
11. Fundacao Universidade de Caxias do Sul β€” United States
12. Hospital Erasto Gaertner- Liga Paranaense de Combate ao Cancer β€” United States
13. IDOR - Regional Bahia β€” United States
14. IDOR - Regional Sao Paulo β€” United States
15. Clinica Medica Sao Germano LTDA β€” United States
16. VUMC Amsterdam β€” United States
17. Albert Schweitzer Ziekenhuis β€” United States
18. Erasmus MC β€” United States
19. Hospital Espanol Auxilio Mutuo Auxilio Mutuo Cancer Center β€” United States
20. Seoul National University Hospital β€” United States
21. The Catholic University of Korea Seoul St Mary s Hospital β€” United States
22. Samsung Medical Center β€” United States
23. Hosp. Univ. Germans Trias I Pujol β€” United States
24. Hosp Clinic de Barcelona β€” United States
25. Hosp. Univ. Virgen de La Arrixaca β€” United States

πŸ“„ Print Doctor Discussion Sheet

Preview and print a 1-page summary with 5 tailored questions for your physician.

πŸ’° Clinical Trial Costs & Insurance Coverage

Coverage for clinical trial participation varies depending on your health insurance policy, state legislation, and whether specific procedures are investigational research or routine medical care. Under federal law (Affordable Care Act Β§ 2709), health insurers generally cannot drop coverage or refuse to pay for routine patient care costs incurred in approved clinical trials.

πŸ’‘ Always ask the study coordinator for the trial's official Informed Consent Form, which outlines all sponsor-funded research items versus procedures billed to your insurance.

πŸ›οΈ Official Government Provenance

NIH ClinicalTrials.gov Protocol Record

NCT Identifier: NCT06500884 β€’ Last Synced: 2026-08-28
View on ClinicalTrials.gov β†—
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