Treatment With Aspirin After Preeclampsia: TAP Trial

🩺 Protocol Summary

The objective of this research project is to conduct a single-site pilot trial to assess the feasibility and effect of low-dose aspirin to augment vascular recovery in the immediate postpartum period after preeclampsia through two specific aims: 1) to pilot test the feasibility of conducting a randomized controlled trial of postpartum low dose aspirin vs. placebo, and 2) to assess the effect of postpartum aspirin on endothelial function and blood pressure. Our central hypothesis is that postpartum administration of low-dose aspirin following preeclampsia will be feasible, improve endothelial function, and lower BP at 6 months postpartum. Subjects will undergo 3 study visits involving BP measurements, blood draws, questionnaires, and/or microiontophoresis. Up to 60 adult subjects will be enrolled at Magee-Women's Hospital.

Primary Research Facility: University of Pittsburgh Magee-Womens Hospital (Pittsburgh, Pennsylvania)

Review these 3 basic logistical and protocol criteria extracted from the public NIH record. (This is a preliminary logistical checklist, not an official clinical eligibility determination).

Diagnosed with, undergoing evaluation for, or seeking treatment related to Hypertensive Disorder of Pregnancy?

🔍 Study Population / Focus Area (Source: Protocol Primary Condition)

Aged between 18 Years and 55 Years? • (Protocol specifies female participants only)

🔍 Protocol Specified Age Range: 18 Years to 55 Years

Able to attend required clinic visits at University of Pittsburgh Magee-Womens Hospital (Pittsburgh, Pennsylvania)?

🔍 Logistical Requirement: Site at University of Pittsburgh Magee-Womens Hospital

📍 Primary Site Map

Site: University of Pittsburgh Magee-Womens Hospital — Pittsburgh, Pennsylvania

💰 Clinical Trial Costs & Insurance Coverage

Coverage for clinical trial participation varies depending on your health insurance policy, state legislation, and whether specific procedures are investigational research or routine medical care. Under federal law (Affordable Care Act § 2709), health insurers generally cannot drop coverage or refuse to pay for routine patient care costs incurred in approved clinical trials.

💡 Always ask the study coordinator for the trial's official Informed Consent Form, which outlines all sponsor-funded research items versus procedures billed to your insurance.