Intravenous vs Oral Acetaminophen in Postoperative Hip Fracture Adult Patients

🩺 Protocol Summary

The INTACT-HIP trial study will evaluate feasibility of conducting a randomized, double-blinded controlled trial comparing postoperative treatment with intravenous (IV) acetaminophen versus oral acetaminophen, in older adults undergoing hip fracture surgery. The results of this feasibility trial will be used to inform designing a larger, multi-center, randomized controlled trial to assess the efficacy of IV acetaminophen compared to oral acetaminophen to reduce delirium and improve other clinical and patient-centered outcomes after hip fracture surgery. It will randomize 42 older adults to receive either oral or IV acetaminophen after hip fracture surgery.

Primary Research Facility: Toronto Western Hospital (UHN) (Toronto, Ontario)

Review these 3 basic logistical and protocol criteria extracted from the public NIH record. (This is a preliminary logistical checklist, not an official clinical eligibility determination).

Diagnosed with, undergoing evaluation for, or seeking treatment related to Hip-fracture?

🔍 Study Population / Focus Area (Source: Protocol Primary Condition)

Aged 60 Years or older?

🔍 Protocol Specified Minimum Age: 60 Years

Able to attend required clinic visits at Toronto Western Hospital (UHN) (Toronto, Ontario)?

🔍 Logistical Requirement: Site at Toronto Western Hospital (UHN)

📍 Primary Site Map

Site: Toronto Western Hospital (UHN) — Toronto, Ontario

💰 Clinical Trial Costs & Insurance Coverage

Coverage for clinical trial participation varies depending on your health insurance policy, state legislation, and whether specific procedures are investigational research or routine medical care. Under federal law (Affordable Care Act § 2709), health insurers generally cannot drop coverage or refuse to pay for routine patient care costs incurred in approved clinical trials.

💡 Always ask the study coordinator for the trial's official Informed Consent Form, which outlines all sponsor-funded research items versus procedures billed to your insurance.