🏛️ Verified NIH Protocol • Sourced via U.S. National Library of Medicine (Last Synced: 2026-05-27)

Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia

🟢 Recruiting Phase 2 💊 Investigational Drug / Biologic Sponsor: Todd C. Lee MD MPH FIDSA

🩺 Protocol Summary

There is a variety of in vitro, in vivo (animal model), and human case series data which suggests that the addition of ertapenem to cefazolin could improve outcomes in methicillin-susceptible S. aureus bacteremia. No randomized controlled trial has been performed. This study is an approved sub-study of The Staphylococcus aureus Network Adaptive Platform (SNAP) trial (NCT05137119)

Primary Research Facility: Foothills Medical Centre (Calgary, Alberta)

📋 Basic Study Criteria & Logistics Checklist

0 of 3 Checked

Review these 3 basic logistical and protocol criteria extracted from the public NIH record. (This is a preliminary logistical checklist, not an official clinical eligibility determination).

Diagnosed with, undergoing evaluation for, or seeking treatment related to Staphylococcus Aureus Bacteremia?

🔍 Study Population / Focus Area (Source: Protocol Primary Condition)

Aged between 18 Years and 100 Years?

🔍 Protocol Specified Age Range: 18 Years to 100 Years

Able to attend required in-person clinic visits and study procedures at one of the participating study centers?

🔍 Logistical Requirement: 6 Registered Participating Sites

📍 Primary Site Map

Site: Foothills Medical Centre — Calgary, Alberta

📍 All Participating Trial Locations (6 Sites)

Multi-Center Trial

This protocol is enrolling participants across multiple clinical centers:

1. Foothills Medical Centre — Calgary, Alberta

2. Hamilton Health Sciences (Hamilton General Hospital and Juravinski Hospital) — Hamilton, Ontario

3. Niagara Health - St. Catharines site — Saint Catharines, Ontario

4. Hospital de la Cité de la Sante — Laval, Quebec

5. Jewish General Hospital — Montreal, Quebec

6. McGill University Health Centre (Royal Victoria Hospital and Montreal General Hospital) — Montreal, Quebec • Contact: (514) 934-1934

📄 Print Doctor Discussion Sheet

Preview and print a 1-page summary with 5 tailored questions for your physician.

💰 Clinical Trial Costs & Insurance Coverage

Coverage for clinical trial participation varies depending on your health insurance policy, state legislation, and whether specific procedures are investigational research or routine medical care. Under federal law (Affordable Care Act § 2709), health insurers generally cannot drop coverage or refuse to pay for routine patient care costs incurred in approved clinical trials.

💡 Always ask the study coordinator for the trial's official Informed Consent Form, which outlines all sponsor-funded research items versus procedures billed to your insurance.

🏛️ Official Government Provenance

NIH ClinicalTrials.gov Protocol Record

NCT Identifier: NCT04886284 • Last Synced: 2026-05-27

View on ClinicalTrials.gov ↗